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These brands contain the same active ingredient (Amoxicillin Trihydrate). Strength and form may differ — confirm substitution with your doctor or pharmacist before switching.
Indications & Uses
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Dosage Adult: 250 mg three times daily, increasing up to 500 mg three times daily for severe infections. Children (up to 10 years of age): 125 mg three times daily, increasing up to 250 mg three times daily for severe infections. Severe or recurrent purulent respiratory infection: 3 gm every 12 hours. Otitis media: the recommended dose is 1 g three times daily for adults and 40 mg/kg body weight daily in 3 divided doses for children (max 3 g daily). Pneumonia: the recommended dose is 500 to 1000 mg three times daily. Dental abscess: the recommended dose is 3 gm, repeated after 10 to 12 hours. Urinary tract infections: the recommended dose is 3 gm, repeated after 10 to 12 hours. Gonorrhoea: a single dose of 2 to 3 gm with Probenecid 1 gm is recommended (Probenecid is contraindicated in children under 2 years). In renal impairment, it may be necessary to reduce the total daily dosage.
Side Effects
Side effects are usually mild and go away on their own. Some people may notice diarrhoea, an upset stomach, or occasionally a skin rash. Rarely, a more serious bowel inflammation called pseudo-membranous colitis has been reported.
Cautions & Contraindications
Warnings & Precautions
The possibility of superinfection with fungal or bacterial pathogens should be kept in mind during treatment. If a superinfection occurs, Simox DS should be stopped and suitable alternative therapy started.
Contraindications
Amoxicillin should not be used by patients who are hypersensitive to penicillin.