Clarithromycin is one of the three medicines in Rabeprazole + Amoxicillin + Clarithromycin, and it has been reported to interact with phenytoin. If you take phenytoin, tell your doctor or pharmacist before starting this combination.
These medicines are often taken together with some care. Your doctor may change a dose, space them apart or check on you more often. Make sure your doctor and pharmacist know you take both.