Methylergonovine Maleate Clarithromycin
ModerateClarithromycin is one of the stronger CYP 3A4 inhibitors. Other medicines in this group include erythromycin and troleandomycin, along with some HIV drugs and azole antifungals such as ketoconazole and itraconazole. CYP 3A4 is the enzyme that breaks down Methylergonovine Maleate, so taking it with clarithromycin can make the body clear Methylergonovine Maleate more slowly.
These medicines are often taken together with some care. Your doctor may change a dose, space them apart or check on you more often. Make sure your doctor and pharmacist know you take both.