Indications
Methylergonovine Maleate is used after the placenta has been delivered, for routine management of uterine atony, hemorrhage and subinvolution of the uterus. It is also used to control uterine hemorrhage in the second stage of labor, after the anterior shoulder has been delivered.
⚠️ Always consult a registered physician before taking any medicine.
Pharmacology
Methylergonovine Maleate acts directly on the smooth muscle of the uterus. It increases the tone, the rate and the strength of the rhythmic contractions. This gives a rapid and sustained tetanic uterotonic effect, so the third stage of labor is shorter and blood loss is reduced.
After I.V. administration the effect starts immediately. After I.M. administration it starts in 2 to 5 minutes, and after oral administration in 5 to 10 minutes.
Pregnancy & Breastfeeding
Methylergonovine is in Pregnancy Category C. Animal reproductive studies haven't been done with it, and it isn't known whether methylergonovine maleate can harm the fetus or affect reproductive capacity. Because of its uterotonic effects, Methylergonovine is contraindicated during pregnancy.
Mothers should not breast-feed while being treated with Methylergonovine, and any milk produced during this time should be discarded. The medicine may cause adverse effects in the breast-feeding infant, and it may also reduce the amount of breast milk. After the last dose, a mother should wait at least 12 hours before starting or resuming breast-feeding.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Dosage Reference
⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.
Side Effects & Interactions
Side Effects
No side-effect data recorded yet.