Sodium Picosulfate + Magnesium Oxide + Citric Acid contains magnesium, which can bind to Tetracycline Hydrochloride in the gut and stop your body from absorbing it properly. This can make the antibiotic work less well. To avoid this, take Tetracycline at least 2 hours before you take Sodium Picosulfate + Magnesium Oxide + Citric Acid, and wait at least 6 hours after it before taking Tetracycline again.
These medicines are often taken together with some care. Your doctor may change a dose, space them apart or check on you more often. Make sure your doctor and pharmacist know you take both.