Sodium Picosulfate + Magnesium Oxide + Citric Acid

Adults: There are two dosing regimens for Sodium Picosulfate + Magnesium Oxide + Citric Acid, and each one needs two separate dosing times. Split-Dose Dosing Regimen (Preferred Method): This is the preferred dosing method. Tell patients to take two separate doses with fluids, as follows. The first dose (1 bottle/1 sachet) is taken in the evening before the colonoscopy (e.g., 5:00 to 9:00 PM). Afterwards, patients drink 1200 ml of clear liquids (5x 240 ml drinks, using the provided measuring cup) before bed, finishing them within 5 hours. The second dose (1 bottle/1 sachet) is taken the next day, about 5 hours before the colonoscopy, followed by at least 720 ml (3x240 ml) of clear liquids. These should be finished within the next 5 hours, but at least 2 hours before the time of the colonoscopy. Day-Before Dosing Regimen (Alternative Method): This is the alternative dosing method, for patients in whom Split-Dosing is inappropriate. Again, tell patients to take two separate doses with fluids. The first dose (1 bottle/1 sachet) is taken in the afternoon or early evening (e.g., 4:00 to 6:00 PM) before the colonoscopy. It is followed by 1200 ml (5x 240 ml, using the provided measuring cup) of clear liquids before the next dose, and these are finished within 5 hours. The second dose (1 bottle/1 sachet) is taken about 6 hours later, in the late evening (e.g., 10:00 PM to 12:00 AM) of the night before the colonoscopy. Patients then drink at least 720 ml (3x240 ml) of clear liquids before bed, again finishing them within 5 hours. In both regimens, patients must drink extra fluids after every dose. Tell them to take only clear liquids (no solid food or milk) on the day before the colonoscopy, right up until 2 hours before the time of the colonoscopy. If a patient has severe bloating, distention or abdominal pain after the first dose, the second dose should be delayed until the symptoms resolve.