Apalutamide Ritonavir
ModerateRitonavir is a strong CYP3A4 inhibitor. That means it slows down one of the main enzymes the body uses to break down Apalutamide, so Apalutamide can stay in the body a little longer. You don't need to lower the Apalutamide dose from the start when the two are used together. If you have side effects or find the combination hard to tolerate, your doctor may consider reducing the Apalutamide dose. Don't change the dose yourself. Let your doctor decide.
These medicines are often taken together with some care. Your doctor may change a dose, space them apart or check on you more often. Make sure your doctor and pharmacist know you take both.