Perkup St. John's Wort Mirtazapine
ModerateMirtazapine has clinically significant interactions with serotonergic drugs, and St. John's wort is one of them. The same warning covers Monoamine Oxidase Inhibitors (MAOI) and the other serotonergic drugs, so the combination with St. John's wort should be treated as a real concern, not a minor one.
These medicines are often taken together with some care. Your doctor may change a dose, space them apart or check on you more often. Make sure your doctor and pharmacist know you take both.