KEZONA Ketoconazole Istradefylline
MajorKetoconazole slows how the body clears Istradefylline, so the Istradefylline dose should not go above 20 mg once a day. Strong medicines that speed up its clearing, such as Rifampicin, should be avoided.
These medicines can affect each other in a serious way. Do not start taking them together unless your doctor has said it is OK. If you already take both, do not stop either one on your own: speak to your doctor or pharmacist soon.
What to do: Do not take these together unless your doctor has said so. If your doctor allows it, follow their instructions exactly.