Nexum Esomeprazole Polymyxin B Sulfate
MajorThe leaflet says polymyxin B should not be used at the same time as, or one after the other with, other drugs that can harm the nerves or kidneys. Esomeprazole is on that list, so the two should be avoided together. The list also names many other medicines, such as gentamicin, cisplatin, ibuprofen and cyclosporine, and those carry the same warning.
These medicines can affect each other in a serious way. Do not start taking them together unless your doctor has said it is OK. If you already take both, do not stop either one on your own: speak to your doctor or pharmacist soon.