Terbiheal Terbinafine Hydrochloride Tramadol Hydrochloride
ModerateCYP2D6 inhibition by terbinafine reduces tramadol activation (less analgesia) and raises serotonergic and seizure risk.
These medicines are often taken together with some care. Your doctor may change a dose, space them apart or check on you more often. Make sure your doctor and pharmacist know you take both.
Clinical management: Monitor analgesic response and adverse effects; consider alternative analgesic.