Pragril 75 Clopidogrel Apalutamide
ModerateApalutamide and clopidogrel can be taken together without changing the starting dose of apalutamide. Clopidogrel is a strong inhibitor of CYP2C8, the enzyme that helps the body process apalutamide. Even so, if apalutamide causes side effects that are hard to tolerate, your doctor may decide to lower the dose.
These medicines are often taken together with some care. Your doctor may change a dose, space them apart or check on you more often. Make sure your doctor and pharmacist know you take both.