Dinogest Dienogest Fluconazole
ModerateFluconazole is one of several CYP3A4 inhibitors (CYP3A4 is the liver enzyme that breaks this drug down) that can push up the amount of Dienogest in your blood. Other inhibitors on the same list include ketoconazole, itraconazole, cimetidine, verapamil, diltiazem, and certain antibiotics and antidepressants. When levels rise, you may get more side effects from Dienogest.
These medicines are often taken together with some care. Your doctor may change a dose, space them apart or check on you more often. Make sure your doctor and pharmacist know you take both.