Pizobet 15 Pioglitazone Abiraterone Acetate
ModerateIn a study in healthy volunteers, taking Pioglitazone together with a single 1,000 mg dose of Zyterone (abiraterone acetate) raised the AUC of Pioglitazone by 46%. AUC is a measure of how much of the medicine stays in the body over time, so this means Pioglitazone builds up more than usual, because the two medicines are handled by the same liver enzyme, CYP2C8.
These medicines are often taken together with some care. Your doctor may change a dose, space them apart or check on you more often. Make sure your doctor and pharmacist know you take both.