Serlin 50 Sertraline Propafenone Hydrochloride
ModerateSertraline is one of several medicines that can raise the level of propafenone in your blood. Because it blocks the CYP2D6 enzyme, it can cause propafenone to build up more than expected. Other drugs that block CYP1A2 (such as amiodarone) or CYP3A4 (such as ketoconazole, ritonavir, saquinavir, erythromycin and grapefruit juice) can do the same.
These medicines are often taken together with some care. Your doctor may change a dose, space them apart or check on you more often. Make sure your doctor and pharmacist know you take both.