Sizopin Clozapine Propafenone Hydrochloride
ModerateClozapine (Sensipin) and propafenone are cleared by the same liver enzyme, so together the body may clear them more slowly and they can build up. Other medicines using this enzyme include some antidepressants and flecainide.
These medicines are often taken together with some care. Your doctor may change a dose, space them apart or check on you more often. Make sure your doctor and pharmacist know you take both.
What to do: Ask your doctor or pharmacist before taking them together. Your doctor will decide any dose change, so do not change doses yourself.