Amilin Amitriptyline Hydrochloride Clomipramine Hydrochloride
ModerateClomipramine and amitriptyline are both tricyclic antidepressants, and the leaflet lists amitriptyline among the medicines for depression that need particular care when taken with clomipramine. It doesn't say what actually happens when the two are combined, only that they interact. The same list also names MAOIs, SSRIs (including any taken within the last 3 weeks) and SNaRIs, but those are separate from this pairing.
These medicines are often taken together with some care. Your doctor may change a dose, space them apart or check on you more often. Make sure your doctor and pharmacist know you take both.