Novastin Simvastatin Fluconazole
MajorRaised simvastatin levels increase risk of myopathy and rhabdomyolysis.
These medicines can affect each other in a serious way. Do not start taking them together unless your doctor has said it is OK. If you already take both, do not stop either one on your own: speak to your doctor or pharmacist soon.
Clinical management: Use lowest simvastatin dose or suspend it; report muscle pain.