Vivori Voriconazole Methylergonovine Maleate
ModerateVoriconazole is one of the azole antifungal medicines that can strongly block the CYP 3A4 enzyme, and when that happens methylergonovine can build up in the body. Other strong CYP 3A4 blockers include certain macrolide antibiotics (erythromycin, troleandomycin, clarithromycin) and HIV protease or reverse transcriptase inhibitors (ritonavir, indinavir, nelfinavir, delavirdine). Ketoconazole and itraconazole, which are also azole antifungals, work the same way.
These medicines are often taken together with some care. Your doctor may change a dose, space them apart or check on you more often. Make sure your doctor and pharmacist know you take both.