Informational only — Not medical advice. Always consult a licensed healthcare provider.

Shasthya স্বাস্থ্য · Health, made simple
বাং
Community data Updated 23 hours ago
🌐 বাংলায় দেখুন

Indications

Trospi is used for the symptomatic treatment of urge incontinence, and for increased urinary frequency and urgency, which can occur in people with overactive bladder (for example idiopathic or neurologic detrusor overactivity).

⚠️ Always consult a registered physician before taking any medicine.

Pharmacology

Trospium chloride is a muscarinic antagonist. It blocks the effect of acetylcholine on muscarinic receptors in organs supplied by cholinergic nerves, and the bladder is one of these. This parasympatholytic action lowers the tonus of the smooth muscle in the bladder. Receptor assays showed that at the concentrations reached with therapeutic doses, trospium chloride has negligible affinity for nicotinic receptors compared with muscarinic receptors.

Pregnancy & Breastfeeding

Studies in animals show no direct or indirect harmful effects on pregnancy, on the development of the embryo or foetus, on childbirth, or on development after birth. In rats, Trospium Chloride does cross the placenta and pass into the mother's milk. For Trospium Chloride 20mg film-coated tablets, there are no clinical data on pregnancies where the medicine was taken. Caution should be taken when prescribing it to pregnant or breastfeeding women.

⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

Dosage Reference

⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.

Adults: The usual dose of Trospium Chloride is one 20 mg tablet twice daily. The doctor should look again at whether you still need the treatment at regular intervals of 3 to 6 months. Swallow the film-coated tablet whole with a glass of water, before meals, on an empty stomach. Renal impairment: for patients with severe renal impairment (CrCl<30 mL/min), the recommended dose is 20 mg once daily at bedtime. In geriatric patients aged 75 years or more, the dose may be reduced to 20 mg once daily, depending on how well the patient tolerates it. Pediatric use: the safety and efficacy of Trospium Chloride 20 mg film-coated tablets in children under 12 years of age have not been established. No data are available.

Side Effects & Interactions

Side Effects

No side-effect data recorded yet.