Community data Updated 23 hours ago

Trifarotene

Topical retinoid and related preparations Prescription

Indications

Acne Vulgaris

Trifarotene cream is a retinoid that you apply to the skin to treat acne vulgaris. It is meant for patients aged 9 years and older.

⚠️ Always consult a registered physician before taking any medicine.

Pharmacology

Trifarotene works as an agonist at the retinoic acid receptors (RAR), and it is particularly active at the gamma subtype of RAR. When these receptors are stimulated, certain target genes are modulated. These genes are linked with several processes, including cell differentiation and the mediation of inflammation. How Trifarotene improves acne is not known exactly.

Pregnancy & Breastfeeding

Trifarotene cream is in Pregnancy Category C. Data from clinical trials in pregnant women who used the cream have not shown a drug-related risk of major birth defects, miscarriage, or harmful outcomes for the mother or the baby.

If you are breastfeeding, think about the benefits of breastfeeding for your baby's development and health, and weigh them against your own clinical need for Trifarotene cream. Also consider any possible harm to the breastfed infant, either from the cream or from the mother's underlying condition.

⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

Dosage Reference

⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.

Adults: Put a thin layer of Trifarotene cream on the affected areas once a day, in the evening, on skin that is clean and dry. A moisturizer is recommended, and you can use it as often as you need from the very start of treatment. Keep the cream away from the eyes, lips, paranasal creases and mucous membranes. Trifarotene cream is for use on the skin only. Don't use it by mouth, in the eyes or in the vagina.