Community data
Updated 2 months ago
Indications
Vaxitet-IG is used to provide short-term (passive) immunity for both preventing and treating tetanus.
⚠️ Always consult a registered physician before taking any medicine.
Pharmacology
Sterile, clear and faintly yellow to brown, this liquid is tetanus antitoxin (equine) for human use. It contains antitoxic globulins that specifically neutralize the toxin produced by Clostridium tetani, obtained by fractionating the serum of horses hyperimmunized against tetanus toxin.
Pregnancy & Breastfeeding
Tetanus Antitoxin (Equine) must not be given during pregnancy.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Dosage Reference
⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.
Adults: Dosage
Prophylaxis of tetanus
Tetanus Antitoxin (equine) should not be used in the routine treatment of traumatic wounds. It is given as prophylaxis to people at risk of tetanus infection from infected or severe wounds. For prophylaxis after injury, people who are non-immune or only partially immune may be given 3,000 to 5,000 units of tetanus antitoxin under the skin (subcutaneously) or into the muscle (intramuscularly). If 24 hours have passed since the wound occurred, the dose is 3,000 III. In crush wounds, or wounds contaminated with soil or other foreign bodies, the dose is 10,000 to 20,000 III. For people below 30 kg, the dose is 1,500 IU. Active immunization with Adsorbed Tetanus vaccine should be given at the same time as this preparation. If the patient has been immunized before, a booster injection of Adsorbed Tetanus vaccine should be given instead.
Treatment
Therapy should be started as soon as possible after the symptoms of the disease appear. The therapeutic dose is not less than 3000 IU. Depending on the severity, the dose may range from 50,000 to 100,000 IU of tetanus antitoxin for hospitalized patients. Part of the dose is given intravenously, and the rest is given intramuscularly.