Indications
Spiramycin is used to treat infections of the respiratory tract, the mouth (buccal cavity), the skin and the soft tissues, when the infection is caused by susceptible organisms. It is also an alternative choice for gonorrhea caused by Neisseria gonorrhoeae in patients who are allergic to the penicillins. Before starting treatment for gonorrhea, the doctor should rule out a possible infection with T. pallidum at the same time.
⚠️ Always consult a registered physician before taking any medicine.
Pharmacology
How macrolides work has been a matter of debate for some time. Spiramycin is a 16-membered macrolide, and it inhibits translocation by binding to the 50S subunits of bacterial ribosomes, with an apparent 1 : 1 stoichiometry. The antibiotic is a potent inhibitor of the binding of both donor and acceptor substrates to the ribosome. Its primary action comes from stimulating the dissociation of peptidyl-tRNA from the ribosomes during translocation.
Pregnancy & Breastfeeding
Nobody has yet established whether Spiramycin is safe to use during pregnancy.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Dosage Reference
⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.