Indications
Sitafloxacin is used for bacterial infections of the throat and airways, including laryngopharyngitis, tonsillitis, acute bronchitis, pneumonia, and secondary infection of chronic respiratory diseases. It is also used for cystitis, pyelonephritis, urethritis and cervicitis. Other uses are otitis media and sinusitis, and infections of the mouth and jaw such as periodontitis, pericoronitis and osteitis of jaw.
⚠️ Always consult a registered physician before taking any medicine.
Pharmacology
Sitafloxacin works against a broad spectrum of bacteria. This covers aerobic and anaerobic Gram-positive and Gram-negative bacteria, and atypical bacteria too. It acts by blocking two bacterial enzymes, DNA gyrase and topoisomerase IV, and this blocking is what gives Sitafloxacin its bactericidal activity. When it was compared with other quinolone antimicrobials, its inhibitory activity against these enzymes was higher. Sitafloxacin also strongly inhibits the same enzymes from quinolone-resistant bacteria.
Pregnancy & Breastfeeding
Pregnancy: Don't use Sitafloxacin in women who are pregnant or who might be pregnant. Its safety in these women has not been established.
Lactation: Nursing mothers should be advised to avoid breast-feeding while they are being treated with Sitafloxacin. In preclinical studies, Sitafloxacin passed into the milk of rats.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Dosage Reference
⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.
Side Effects & Interactions
Side Effects
No side-effect data recorded yet.