Pricing
Prices are indicative MRP and may vary by pharmacy. Trend compares against the last recorded price.
All price changes →Indications & Uses
Sitaquin is indicated for:
Pharmacology
Sitafloxacin works against a broad spectrum of bacteria. This covers aerobic and anaerobic Gram-positive and Gram-negative bacteria, and atypical bacteria too. It acts by blocking two bacterial enzymes, DNA gyrase and topoisomerase IV, and this blocking is what gives Sitafloxacin its bactericidal activity. When it was compared with other quinolone antimicrobials, its inhibitory activity against these enzymes was higher. Sitafloxacin also strongly inhibits the same enzymes from quinolone-resistant bacteria.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
The recommended dose of Sitafloxacin is 50 mg twice daily or 100 mg once daily, for all indications. The length of treatment depends on the infection. Laryngopharyngitis, acute bronchitis and tonsillitis need 3 to 7 days. Pneumonia and secondary infections of chronic respiratory diseases need 7 days. Acute cystitis needs 3 days, while acute pyelonephritis and complicated urinary tract infection need 7 to 14 days. Urethritis and cervicitis need 7 days. Acute otitis media and sinusitis need 7 days, and so does acute exacerbation of chronic otitis media and sinusitis. For periodontitis, pericoronitis and osteitis of jaw, the course is 3 to 7 days. If a patient is suspected of having a poor response to the usual dosage, the Sitafloxacin 50 mg tablet dose may be increased to 100 mg, taken orally twice daily. It is not for use by children under 18 years. In renal and hepatic impaired patients, the medicine should be given with care, and if any abnormal symptoms occur, it should be discontinued and appropriate measures taken.
Side Effects
The side effects people report most often with Sitafloxacin are rash, dizziness, headache, diarrhea, loose stool, stomach discomfort, abdominal bloating, abdominal pain, constipation, indigestion, nausea and stomatitis. If you notice any of these, talk to your doctor or pharmacist.
Cautions & Contraindications
Warnings & Precautions
Sitafloxacin should be used with caution in patients who have a convulsive disease such as epilepsy, or who have had one in the past. The same care applies to patients with myasthenia gravis and to those who also have an aortic aneurysm or aortic dissection. Patients need this caution too if they have had an aortic aneurysm or aortic dissection before, if it runs in the family, or if they have risk factors for either condition. Elderly patients generally have reduced physiological function.
Contraindications
Sitafloxacin must not be given to patients who have had a hypersensitivity reaction to any ingredient of Sitafloxacin or to other quinolones. It is also contraindicated in pediatric patients. The safety of Sitafloxacin has not been established in low-birth-weight infants, newborn infants, infants and toddlers, children and adolescents.
Pregnancy & Breastfeeding
Pregnancy: Don't use Sitafloxacin in women who are pregnant or who might be pregnant. Its safety in these women has not been established.
Lactation: Nursing mothers should be advised to avoid breast-feeding while they are being treated with Sitafloxacin. In preclinical studies, Sitafloxacin passed into the milk of rats.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Overdose
Phototoxicity was seen after exposure to ultraviolet irradiation in people who took Sitafloxacin by mouth at 500 mg once or twice daily. When Sitafloxacin was given intravenously at 400 to 800 mg twice daily, the QT interval became longer in a dose-dependent way, with a mean fluctuation range of 10 msec or less.
⚠️ In an emergency call 999 or go to the nearest hospital emergency department.
Storage
Keep Sitafloxacin at or below 25°C, and away from light. Always store it where children can't reach it.
Drug Interactions
Common questions about Sitaquin 50 mg
What is Sitaquin 50 mg Tablet?
Sitaquin 50 mg Tablet is a medicine that contains Sitafloxacin. It is made by Ziska Pharmaceuticals Ltd. It belongs to the Fourth generation cephalosporins group of medicines.
What is Sitaquin used for?
Sitaquin is used for: Pneumonia, Bronchitis, Sinusitis, Tonsillitis, Bacterial Infection, Urinary Tract Infection, Otitis Media.
What are the side effects of Sitaquin?
The side effects people report most often with Sitafloxacin are rash, dizziness, headache, diarrhea, loose stool, stomach discomfort, abdominal bloating, abdominal pain, constipation, indigestion, nausea and stomatitis. If you notice any of these, talk to your doctor or pharmacist.
Can I take Sitaquin during pregnancy or while breastfeeding?
Pregnancy: Don't use Sitafloxacin in women who are pregnant or who might be pregnant. Its safety in these women has not been established. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
What happens if I take too much Sitaquin?
Phototoxicity was seen after exposure to ultraviolet irradiation in people who took Sitafloxacin by mouth at 500 mg once or twice daily. When Sitafloxacin was given intravenously at 400 to 800 mg twice daily, the QT interval became longer in a dose-dependent way, with a mean fluctuation range of 10 msec or less. In an emergency call 999 or go to the nearest hospital emergency department.
How should I store Sitaquin?
Keep Sitafloxacin at or below 25°C, and away from light. Always store it where children can't reach it.
Can I take other medicines with Sitaquin?
Some medicines can interact with Sitafloxacin, for example: Ketoprofen, Iron, Magnesium. Tell your doctor or pharmacist about every medicine you take.
Is there a cheaper medicine with the same ingredient?
Sitaquin is already among the lowest-priced brands of Sitafloxacin at this strength.
Do I need a prescription for Sitaquin?
Sitaquin is a prescription (Rx) medicine. Take it as your doctor advises.