Indications
Rupatadine Fumarate is used to relieve the symptoms of seasonal and perennial allergic rhinitis, and of urticaria.
⚠️ Always consult a registered physician before taking any medicine.
Pharmacology
Rupatadine is a long-acting antagonist of histamine H1-receptors, and it doesn't cause sedation. It also blocks platelet activating factor (PAF). Both histamine and PAF cause broncho constriction, which leads to an increase in vascular permeability, and both act as mediators in the inflammatory process. Because Rupatadine works in these two ways, it shows a better therapeutic effect than an antihistamine that acts alone.
Rupatadine has other anti allergic properties too. It inhibits the degranulation of mast cells, whether the trigger is immunological or non immunological. It also inhibits the release of cytokines, particularly tumor necrosis factor alpha (TNF α), in human mastocytes and monocytes.
Pregnancy & Breastfeeding
There is no clinical data on the use of Rupatadine in pregnancy, so pregnant women should not take it unless the possible benefit is greater than the possible risk to the infant. It is also not known whether Rupatadine passes into breast milk. For that reason it shouldn't be used while breastfeeding, unless the possible benefit to the mother justifies the possible risk to the infant.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Dosage Reference
⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.
Side Effects & Interactions
Side Effects
No side-effect data recorded yet.