Indications
Celbarin, when combined with Peginterferon alfa-2a or Interferon alfa, is used to treat chronic hepatitis C (CHC) infection in patients aged 5 years and older who have compensated liver disease and have not previously received interferon alpha treatment. Celbarin is not effective when used alone and should never be taken as a standalone therapy.
⚠️ Always consult a registered physician before taking any medicine.
Pharmacology
Ribavirin is a man-made (synthetic) nucleoside that works against several viruses, including respiratory syncytial virus, influenza virus and herpes simplex virus. Exactly how it works is not fully understood. It is thought to act at more than one site in the cell, including certain cellular enzymes, to interfere with the virus's ability to build its nucleic acid. Its mono- and triphosphate forms are the derivatives known to be responsible for this antiviral effect.
Pregnancy & Breastfeeding
Pregnancy: Pregnant women, and women who are expecting a child, must not use Ribavirin because the drug may have a teratogenic effect. Male patients and their female partners of childbearing age need to be counselled to use 2 forms of effective contraception during treatment with Ribavirin and for 6 months after treatment has ended. Don't start Ribavirin until a negative pregnancy test report has been obtained, taken immediately before therapy begins. Patients must then do a pregnancy test every month during therapy and for 6 months after it.
Brestfeeding: Nobody knows whether Ribavirin passes into human milk. Because it could cause adverse reactions in nursing infants, a decision should be made either to stop nursing or not to start therapy.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Dosage Reference
⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.
Side Effects & Interactions
Side Effects
No side-effect data recorded yet.