Informational only — Not medical advice. Always consult a licensed healthcare provider.

Shasthya স্বাস্থ্য · Health, made simple
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Community data Updated 23 hours ago

Regular Insulin Human + Isophane Insulin Human

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Indications

Type 2 Diabetes Mellitus Type 1 Diabetes Mellitus Diabetes Mellitus

Regular Insulin Human + Isophane Insulin Human injection is used for the treatment of all patients with type 1 diabetes. It is also used for patients with type 2 diabetes who are not adequately controlled by diet and/or oral hypoglycemic agents. The injection is used for the initial stabilization of diabetes in patients with diabetic ketoacidosis or hyperosmolar non-ketotic syndrome, and during periods of stress such as severe infections and major surgery in diabetic patients. Regular Insulin Human + Isophane Insulin Human is also indicated for the treatment of gestational diabetes.

⚠️ Always consult a registered physician before taking any medicine.

Pharmacology

Regular Insulin Human + Isophane Insulin Human lowers blood glucose because insulin binds to receptors on muscle and fat cells, and this helps those cells take up glucose. At the same time, it holds back the release of glucose from the liver. Insulin has a half-life of a few minutes in the blood stream, and it doesn't bind to plasma proteins to any great extent. After a subcutaneous injection, the average action profile is as follows: onset of action within 30 minutes, peak plasma levels reached between 1 to 3 hours, and duration of action of approximately 18 to 24 hours.

Pregnancy & Breastfeeding

Insulin can be used to treat diabetes during pregnancy without restriction, because it does not cross the placental barrier. What does harm is poorly controlled diabetes. Both hypoglycemia and hyperglycemia, which can happen when therapy is inadequate, raise the risk of malformations and of death in utero.

Insulin requirements usually fall in the first trimester, then rise through the second and third trimesters. After delivery they go back quickly to the values seen before pregnancy.

A nursing mother can take insulin without any risk to her baby. Her insulin dosage, her diet or both may still need to be adjusted.

⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

Dosage Reference

⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.

Adults: The dosage of Regular Insulin Human + Isophane Insulin Human is individual, and the doctor decides it according to the needs of the patient. For type 1 diabetic patients on maintenance therapy, the average total daily insulin requirement lies between 0.5 and 1.0 IU/Kg. In pre-pubertal children it usually varies from 0.7 to 1.0 IU/Kg. The daily requirement may be higher in patients with insulin resistance (for example during puberty in the young, or due to obesity). It may be lower in patients with endogenous insulin production, or during the period of partial remission. The initial dosage for type 2 diabetic patients is often lower, for example 0.3 to 0.6 IU/Kg/Day. An injection should be followed within 30 minutes by a meal or snack containing carbohydrates.

Side Effects & Interactions

Side Effects

No side-effect data recorded yet.