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Rx30%+70% • SC Injection
More from Maxsulin
Other strengths and forms by Incepta Pharmaceuticals Ltd.
Indications & Uses
Maxsulin is indicated for:
Pharmacology
Regular Insulin Human + Isophane Insulin Human lowers blood glucose because insulin binds to receptors on muscle and fat cells, and this helps those cells take up glucose. At the same time, it holds back the release of glucose from the liver. Insulin has a half-life of a few minutes in the blood stream, and it doesn't bind to plasma proteins to any great extent. After a subcutaneous injection, the average action profile is as follows: onset of action within 30 minutes, peak plasma levels reached between 1 to 3 hours, and duration of action of approximately 18 to 24 hours.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
The dosage of Regular Insulin Human + Isophane Insulin Human is individual, and the doctor decides it according to the needs of the patient. For type 1 diabetic patients on maintenance therapy, the average total daily insulin requirement lies between 0.5 and 1.0 IU/Kg. In pre-pubertal children it usually varies from 0.7 to 1.0 IU/Kg. The daily requirement may be higher in patients with insulin resistance (for example during puberty in the young, or due to obesity). It may be lower in patients with endogenous insulin production, or during the period of partial remission. The initial dosage for type 2 diabetic patients is often lower, for example 0.3 to 0.6 IU/Kg/Day. An injection should be followed within 30 minutes by a meal or snack containing carbohydrates.
Side Effects
Most side effects seen in people using human insulin depend on the dose and come from the way insulin works in the body. As with other insulin products, hypoglycemia is generally the most common unwanted effect. It can happen when the insulin dose is too high for what the body needs. Lipodystrophy may develop at the injection site if the site isn't rotated within an area. Generalized hypersensitivity can show up as a skin rash over the body, itching, sweating, gastrointestinal upset and angioneurotic oedema. Difficulty in breathing, palpitation and a fall in blood pressure can also occur. These generalized reactions are potentially life threatening. Oedema may appear when insulin therapy is first started. These symptoms usually pass after a short time.
Cautions & Contraindications
Warnings & Precautions
If the dose is too low, or treatment is stopped, hyperglycemia can follow, especially in type 1 diabetes. In type 1 diabetes, hyperglycemia that goes untreated eventually leads to diabetic ketoacidosis, which can be lethal. Hypoglycemia may occur if the insulin dose is too high for what the body needs. Transferring a patient to another type or brand of insulin should be done under strict medical supervision. A change in strength, brand (manufacturer), type (rapid acting insulin, dual acting insulin, intermediate and long acting insulin etc.), species (animal, human insulin analogue) or method of manufacture (recombinant DNA versus animal source insulin) may mean the dose has to change. Before travelling between different time zones, patients should be advised to talk to their doctor, because they may have to take insulin and meals at different times. Don't use this insulin if there are clumps in it after mixing. Don't use it either if solid white particles stick to the bottom or wall of the bottle and give it a frosted look.
Contraindications
Regular Insulin Human + Isophane Insulin Human must never be given to a patient who has hypoglycemia, or to anyone who is hypersensitive to human insulin or to any of the excipients.
Pregnancy & Breastfeeding
Insulin can be used to treat diabetes during pregnancy without restriction, because it does not cross the placental barrier. What does harm is poorly controlled diabetes. Both hypoglycemia and hyperglycemia, which can happen when therapy is inadequate, raise the risk of malformations and of death in utero.
Insulin requirements usually fall in the first trimester, then rise through the second and third trimesters. After delivery they go back quickly to the values seen before pregnancy.
A nursing mother can take insulin without any risk to her baby. Her insulin dosage, her diet or both may still need to be adjusted.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Overdose
Insulins don't have a specific overdose definition. The main danger is hypoglycemia, and it can develop in stages. A mild episode can be treated by giving glucose or sugary products by mouth. A severe episode, where the patient has become unconscious, can be treated with Glucagon (0.5 to 1 mg) given intramuscularly or subcutaneously by a trained person, or with glucose given intravenously by a medical professional. If the patient doesn't respond to Glucagon within 10 to 15 minutes, glucose must also be given intravenously. Once the patient regains consciousness, oral carbohydrate is recommended to prevent a relapse.
⚠️ In an emergency call 999 or go to the nearest hospital emergency department.
Storage
Store Regular Insulin Human + Isophane Insulin Human between 2°C and 8°C, which means in a refrigerator. Don't use any insulin that has been frozen. Keep the cartridge in its outer carton so light doesn't reach it, and protect it from too much heat and from sunlight.
Once a cartridge is in use, don't put it in the refrigerator. It can be used for up to 6 weeks if kept below 25°C, or for 4 weeks if kept below 30°C.
Mix the preparation well before use, preferably by rolling the cartridge slowly between your hands.
Drug Interactions
Common questions about Maxsulin 30%+70%
What is Maxsulin 30%+70% SC Injection?
Maxsulin 30%+70% SC Injection is a medicine that contains Regular Insulin Human + Isophane Insulin Human. It is made by Incepta Pharmaceuticals Ltd.
What is Maxsulin used for?
Maxsulin is used for: Type 2 Diabetes Mellitus, Type 1 Diabetes Mellitus, Diabetes Mellitus.
What are the side effects of Maxsulin?
Most side effects seen in people using human insulin depend on the dose and come from the way insulin works in the body. As with other insulin products, hypoglycemia is generally the most common unwanted effect.
Can I take Maxsulin during pregnancy or while breastfeeding?
Insulin can be used to treat diabetes during pregnancy without restriction, because it does not cross the placental barrier. What does harm is poorly controlled diabetes. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
What happens if I take too much Maxsulin?
Insulins don't have a specific overdose definition. The main danger is hypoglycemia, and it can develop in stages. In an emergency call 999 or go to the nearest hospital emergency department.
How should I store Maxsulin?
Store Regular Insulin Human + Isophane Insulin Human between 2°C and 8°C, which means in a refrigerator. Don't use any insulin that has been frozen.
Can I take other medicines with Maxsulin?
Some medicines can interact with Regular Insulin Human + Isophane Insulin Human, for example: Danazol, Insulin (Human) 30/70, Octreotide Acetate. Tell your doctor or pharmacist about every medicine you take.
Do I need a prescription for Maxsulin?
Maxsulin is a prescription (Rx) medicine. Take it as your doctor advises.