Informational only — Not medical advice. Always consult a licensed healthcare provider.

Community data Updated 23 hours ago

Indications

Rasagil tablet (rasagiline) is used to treat Parkinson's disease (PD). Doctors can prescribe it on its own as monotherapy, or along with other treatment as adjunct therapy.

⚠️ Always consult a registered physician before taking any medicine.

Pharmacology

Rasagiline is an irreversible inhibitor of monoamine oxidase. Doctors use it on its own in early Parkinson's disease, or as an add-on treatment in more advanced cases. It works through its MAO-B inhibitory activity, which raises the extracellular level of dopamine in the striatum. This higher dopamine level and the increased dopaminergic activity that follows are likely to be behind the benefit seen with rasagiline in models of dopaminergic motor dysfunction.

Pregnancy & Breastfeeding

Rasagiline is in pregnancy category C, so a doctor should be careful when prescribing it to a pregnant woman. Experimental data showed that Rasagiline inhibits prolactin secretion, which means it may also inhibit lactation. Nobody knows yet whether Rasagiline passes into human milk. For that reason, take care when giving it to a breastfeeding mother.

⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

Dosage Reference

⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.

Adults: The recommended dose of Rasagiline is 1 mg by mouth once daily, either on its own or as an add-on in patients who are not taking levodopa. For patients taking levodopa, with or without other PD drugs (for example a dopamine agonist, amantadine or anticholinergics), the starting dose is 0.5 mg once daily. If the patient tolerates 0.5 mg a day but the clinical response is not sufficient, the dose may be increased to 1 mg once daily. When Rasagiline is given together with levodopa, the levodopa dose may be reduced, depending on how the individual patient responds. The recommended dose should not be exceeded because of the risk of hypertension. Pediatric use: Safety and effectiveness in children have not been established. Geriatric use: No significant differences in the safety profile were seen between elderly and non-elderly patients.

Side Effects & Interactions