Pharmacology
Quinine is believed to interfere with protein metabolism in malarial parasites, and it also inhibits their nucleic acid synthesis. It is a highly active blood schizonticide, which means it suppresses the asexual cycle of development of the parasites inside the erythrocytes. Quinine works both as a suppressive drug and in the overt clinical attack of malaria.
Pregnancy & Breastfeeding
Quinine Sulfate isn't necessarily ruled out in pregnancy. At the usual therapeutic dose it is considered safe for pregnant women. Only a very small amount passes into breast milk, and that amount is not enough to rule out its use while breastfeeding.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.