More from Kanaquine
Other strengths and forms by Globe Pharmaceuticals Ltd.
Indications & Uses
Quin is used for uncomplicated, severe and complicated falciparum malaria, and for falciparum malaria that has become resistant to other drugs. It is also used for the prevention of nocturnal muscle cramps, and for the alleviation of muscle cramps in Thomsen's disease.
Pharmacology
Quinine is believed to interfere with protein metabolism in malarial parasites, and it also inhibits their nucleic acid synthesis. It is a highly active blood schizonticide, which means it suppresses the asexual cycle of development of the parasites inside the erythrocytes. Quinine works both as a suppressive drug and in the overt clinical attack of malaria.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Adults take 600 mg of quinine salt by mouth every 8 hours for 7 days. If the patient is seriously ill, quinine sulfate should be given by intravenous infusion instead. The adult infusion starts with a loading dose of 20 mg/kg of quinine salt (up to a maximum of 1.4 g), infused over 4 hours. After 8 to 12 hours, a maintenance dose of 10 mg/kg of quinine salt (up to a maximum of 700 mg) is infused over 4 hours, and this is repeated every 8 to 12 hours. The infusions continue until the patient can swallow tablets and finish the 7-day course.
Children tolerate quinine well. By mouth, the dose for children is 10 mg/kg of quinine salt every 8 hours for 7 days. For intravenous infusion, the dose for children is worked out on a mg/kg basis, the same as for adults.
In pregnancy, the adult treatment doses given above, both oral and intravenous (including the loading dose), can safely be given to pregnant women.
Side Effects
Quinine Sulfate can cause cinchonism, which includes tinnitus, headache, nausea and visual disturbances. Blood disorders and skin reactions may also occur.
Cautions & Contraindications
Warnings & Precautions
Take extra care with Quinine Sulfate in people who have severe heart disease, myasthenia gravis or diabetes mellitus. When it is given as an IV injection, give it slowly. Using Mefloquine together with Quin sulphate may increase the chance of side effects.
Pregnancy & Breastfeeding
Quinine Sulfate isn't necessarily ruled out in pregnancy. At the usual therapeutic dose it is considered safe for pregnant women. Only a very small amount passes into breast milk, and that amount is not enough to rule out its use while breastfeeding.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Storage
Taking Mefloquine together with Quin sulphate may raise the chance of side effects.
Common questions about Kanaquine 300 mg
What is Kanaquine 300 mg Injection?
Kanaquine 300 mg Injection is a medicine that contains Quinine Sulfate. It is made by Globe Pharmaceuticals Ltd. It belongs to the Anti-malarial drugs group of medicines.
What is Kanaquine used for?
Quin is used for uncomplicated, severe and complicated falciparum malaria, and for falciparum malaria that has become resistant to other drugs. It is also used for the prevention of nocturnal muscle cramps, and for the alleviation of muscle cramps in Thomsen's disease.
What are the side effects of Kanaquine?
Quinine Sulfate can cause cinchonism, which includes tinnitus, headache, nausea and visual disturbances. Blood disorders and skin reactions may also occur.
Can I take Kanaquine during pregnancy or while breastfeeding?
Quinine Sulfate isn't necessarily ruled out in pregnancy. At the usual therapeutic dose it is considered safe for pregnant women. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
How should I store Kanaquine?
Taking Mefloquine together with Quin sulphate may raise the chance of side effects.
Do I need a prescription for Kanaquine?
Kanaquine is a prescription (Rx) medicine. Take it as your doctor advises.