Pyridostigmine Bromide

Adults: Adults take Pyridostigmine Bromide by mouth in doses of 60 to 120 mg (1 or 2 tablets) at intervals through the day. These doses are given when maximum strength is needed, for example on rising and before mealtimes. A dose usually works for three to four hours in the daytime, but a dose taken on retiring for bed often lasts longer (six hours). The total daily dose is usually 5 to 20 tablets, though some patients may need more than that. For newborn infants, the dose of Pyridostigmine ranges from 5 to 10 mg orally every four hours, given 30 to 60 minutes before feeding. Treatment is not usually needed beyond eight weeks of age, except in the rare conditions of congenital and familial infantile myasthenia. For older children, those under 6 years old should start with half a tablet (30 mg), and children 6 to 12 years old with one tablet (60 mg). The dose should be raised gradually, in steps of 15 to 30 mg daily, until the best improvement is reached. Total daily requirements are usually 30 to 360 mg by mouth.