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Other brands with the same active ingredient
These brands contain the same active ingredient (Pyridostigmine Bromide). Same strength and form. Confirm the switch with your doctor or pharmacist.
Indications & Uses
Pyridostigmine Bromide is used to treat myasthenia gravis, paralytic ileus and postoperative urinary retention.
Pharmacology
Pyridostigmine tablet is a cholinesterase inhibitor that works when taken by mouth. It stops cholinesterase from breaking down acetylcholine, so nerve impulses pass more freely across the neuromuscular junction. Pyridostigmine is an analog of neostigmine, but the two differ in some clinically significant ways. Pyridostigmine acts for longer and causes fewer gastrointestinal side effects.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Adults take Pyridostigmine Bromide by mouth in doses of 60 to 120 mg (1 or 2 tablets) at intervals through the day. These doses are given when maximum strength is needed, for example on rising and before mealtimes. A dose usually works for three to four hours in the daytime, but a dose taken on retiring for bed often lasts longer (six hours). The total daily dose is usually 5 to 20 tablets, though some patients may need more than that.
For newborn infants, the dose of Pyridostigmine ranges from 5 to 10 mg orally every four hours, given 30 to 60 minutes before feeding. Treatment is not usually needed beyond eight weeks of age, except in the rare conditions of congenital and familial infantile myasthenia.
For older children, those under 6 years old should start with half a tablet (30 mg), and children 6 to 12 years old with one tablet (60 mg). The dose should be raised gradually, in steps of 15 to 30 mg daily, until the best improvement is reached. Total daily requirements are usually 30 to 360 mg by mouth.
Side Effects
Most side effects of Pyridostigmine Bromide come from taking too much of it, and they fall into two types, muscarinic and nicotinic. The muscarinic ones include nausea, vomiting, diarrhea, abdominal cramps, increased peristalsis, increased salivation, increased bronchial secretions, miosis and diaphoresis. The nicotinic ones are mainly muscle cramps, fasciculation and weakness. Atropine can usually counteract the muscarinic side effects, but for the reasons given in the preceding section, using it this way is not without danger. Like any compound that contains the bromide radical, Pyridostigmine Bromide may cause a skin rash in an occasional patient. These reactions usually clear up quickly once the medicine is stopped.
Cautions & Contraindications
Warnings & Precautions
Pyridostigmine Bromide leaves the body mostly unchanged through the kidneys. So people with kidney disease may need lower doses, and the dose should be adjusted step by step until the right effect is reached.
Contraindications
Pyridostigmine must not be used when there is a mechanical blockage of the intestine or the urinary tract. Doctors should be especially careful when giving it to patients with bronchial asthma. If atropine is used to counter the side effects of pyridostigmine, that too needs care.
Pregnancy & Breastfeeding
Nobody has established whether Pyridostigmine is safe to use during pregnancy or while breastfeeding.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Storage
Keep Pyridostigmine Bromide in a cool, dry place, away from light. Keep it out of children's reach.
Drug Interactions
Common questions about Pyrostig 60 mg
What is Pyrostig 60 mg Tablet?
Pyrostig 60 mg Tablet is a medicine that contains Pyridostigmine Bromide. It is made by Popular Pharmaceuticals PLC. It belongs to the Drugs used in Myasthenia Gravis group of medicines.
What is Pyrostig used for?
Pyridostigmine Bromide is used to treat myasthenia gravis, paralytic ileus and postoperative urinary retention.
What are the side effects of Pyrostig?
Most side effects of Pyridostigmine Bromide come from taking too much of it, and they fall into two types, muscarinic and nicotinic. The muscarinic ones include nausea, vomiting, diarrhea, abdominal cramps, increased peristalsis, increased salivation, increased bronchial secretions, miosis and diaphoresis.
Can I take Pyrostig during pregnancy or while breastfeeding?
Nobody has established whether Pyridostigmine is safe to use during pregnancy or while breastfeeding. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
How should I store Pyrostig?
Keep Pyridostigmine Bromide in a cool, dry place, away from light. Keep it out of children's reach.
Can I take other medicines with Pyrostig?
Some medicines can interact with Pyridostigmine Bromide, for example: Methocarbamol, Mefloquine, Pyridostigmine, Dexpanthenol. Tell your doctor or pharmacist about every medicine you take.
Is there a cheaper medicine with the same ingredient?
Dostimid by Unimed Unihealth Pharmaceuticals Ltd. has the same ingredient and strength for ৳25.00 per unit, compared with ৳25.09 for Pyrostig. Ask your doctor or pharmacist before switching.
Do I need a prescription for Pyrostig?
Pyrostig is a prescription (Rx) medicine. Take it as your doctor advises.