Indications
Pitavastatin Calcium is used alongside diet in people with primary hyperlipidemia and mixed dyslipidemia. It helps lower raised total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), apolipoprotein B (Apo B) and triglycerides (TG), and it helps raise high-density lipoprotein cholesterol (HDL-C).
⚠️ Always consult a registered physician before taking any medicine.
Pharmacology
Pitavastatin works by competitively inhibiting HMG-CoA reductase, the rate-determining enzyme in the making of cholesterol. It competes with the substrate for the enzyme, and this blocks cholesterol synthesis in the liver. The liver then produces more LDL-receptors, so more LDL is taken up from the blood into the liver, and plasma TC falls. Pitavastatin also keeps cholesterol synthesis in the liver suppressed over time, and this lowers the levels of very low density lipoproteins.
Pregnancy & Breastfeeding
Pitavastatin is Pregnancy Category X, so it must not be used by women who are pregnant or who may become pregnant. Nobody knows yet whether pitavastatin passes into human breast milk. Another medicine in the same class has been shown to pass a small amount into milk, though. For this reason, women who need treatment with pitavastatin should be advised not to breastfeed their infants, or to stop pitavastatin.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Dosage Reference
⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.
Side Effects & Interactions
Side Effects
No side-effect data recorded yet.