Indications
Pefloxacin Mesylate Dihydrate is indicated in adults for the treatment of a single infection, or mixed infections caused by two or more susceptible microorganisms. It can also be used when the infection is caused by organisms that are resistant to other antibiotics. Pefloxacin Mesylate Dihydrate is indicated for the following conditions. Gastrointestinal infection: enteric fever, acute bacterial diarrhoea and chronic Salmonella carriers. Urinary tract infection: cystitis, pyelonephritis, prostatitis, epididymitis, and uncomplicated and complicated urethritis. Respiratory tract infection: pneumonia, acute and chronic bronchitis, cystic fibrosis, bronchiectasis and empyema. Ear, nose and throat infection: otitis media, otitis externa, sinusitis and tonsillitis. Bone and joint infection: osteomyelitis and arthritis. Skin and soft tissue infection: infected ulcer, wound infection, abscess, cellulitis, erysipelas and infected burn. Pelvic infection: salpingitis, endometritis and pelviperitonitis. Abdominal and hepatobiliary infection: peritonitis, intra abdominal abscess, cholingitis, cholecystitis and empyema of the gall bladder. It is also used in septicemia, bacteraemia, gonorrhoea, endocarditis and meningitis.
⚠️ Always consult a registered physician before taking any medicine.
Pharmacology
Pefloxcin is a synthetic antibacterial medicine that belongs to the fluoroquinolone group. It works by inhibiting the subunit-A of DNA gyrase (Topoisomerase II). Pefloxcin kills bacteria, which makes it bactericidal, and it acts against a broad spectrum of them.
Pregnancy & Breastfeeding
The FDA has placed pefloxacin in pregnancy category C.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Dosage Reference
⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.
Side Effects & Interactions
Side Effects
No side-effect data recorded yet.