Indications
Paliperidone extended release tablet is used for schizophrenia, both for acute treatment and for preventing the illness from coming back. It is also used in the treatment of schizoaffective disorder, either as monotherapy or together with antidepressants or mood stabilizers.
⚠️ Always consult a registered physician before taking any medicine.
Pharmacology
Paliperidone is a psychotropic medicine from the chemical class of benzisoxazole derivatives. It is the major active metabolite of Risperidone. In the brain it works as a dopamine Type 2 (D2) antagonist, and its serotonin Type 2 (5-HT2A) antagonist activity is the stronger part of its action. Paliperidone also blocks α1 and α2 adrenergic receptors and H1 histaminergic receptors, which may explain some of its other effects. It has no affinity for cholinergic muscarinic receptors or for β1 and β2 adrenergic receptors.
Pregnancy & Breastfeeding
Paliperidone is a Pregnancy Category C medicine. There are no adequate and well-controlled studies in pregnant women, so it should be used during pregnancy only if the possible benefit justifies the possible risk to the fetus.
Paliperidone passes into human breast milk. The known benefits of breastfeeding should be weighed against the unknown risks of the baby being exposed to paliperidone.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Side Effects & Interactions
Side Effects
No side-effect data recorded yet.