Indications & Uses
Modesto XR 1.5 is indicated for:
Pharmacology
Paliperidone is a psychotropic medicine from the chemical class of benzisoxazole derivatives. It is the major active metabolite of Risperidone. In the brain it works as a dopamine Type 2 (D2) antagonist, and its serotonin Type 2 (5-HT2A) antagonist activity is the stronger part of its action. Paliperidone also blocks α1 and α2 adrenergic receptors and H1 histaminergic receptors, which may explain some of its other effects. It has no affinity for cholinergic muscarinic receptors or for β1 and β2 adrenergic receptors.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Detailed dosing reference is not available yet. Please follow your prescription and consult your pharmacist.
Side Effects
The most common side effects of Paliperidone are tachycardia (a fast heartbeat), akathisia, somnolence, tremor, dystonia, cogwheel rigidity, anxiety, weight increase, dyspepsia, constipation and nasopharyngitis, among others.
Cautions & Contraindications
Warnings & Precautions
Doctors should take care when prescribing Paliperidone for people who already have cardiovascular disease, QT prolongation, neuroleptic malignant syndrome, tardive dyskinesia, hyperglycemia, dyslipidemia, obesity, hyperprolactinemia, leukopenia, neutropenia, agranulocytosis or seizures. Care is also needed where there is a potential for cognitive and motor impairment, and in similar conditions.
Pregnancy & Breastfeeding
Paliperidone is a Pregnancy Category C medicine. There are no adequate and well-controlled studies in pregnant women, so it should be used during pregnancy only if the possible benefit justifies the possible risk to the fetus.
Paliperidone passes into human breast milk. The known benefits of breastfeeding should be weighed against the unknown risks of the baby being exposed to paliperidone.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Use in Special Populations
Use of Paliperidone in children has not been established as safe or effective for every age group. For schizophrenia, safety and effectiveness have not been established in patients under 12 years of age. For schizoaffective disorder, they have not been established in patients under 18 years of age.
Overdose
Information on Paliperidone overdose is limited, and there is no specific antidote for it. If an overdose happens, the usual supportive measures are used, along with treatment for whatever symptoms appear.
⚠️ In an emergency call 999 or go to the nearest hospital emergency department.
Storage
Keep Paliperidone in a cool, dry place, away from light. Make sure children can't reach it.
Drug Interactions
Common questions about Modesto XR 1.5 1.5 mg
What is Modesto XR 1.5 1.5 mg Er Tablet?
Modesto XR 1.5 1.5 mg Er Tablet is a medicine that contains Paliperidone. It is made by Incepta Pharmaceuticals Ltd. It belongs to the Atypical neuroleptic drugs group of medicines.
What is Modesto XR 1.5 used for?
Modesto XR 1.5 is used for: Schizophrenia.
What are the side effects of Modesto XR 1.5?
The most common side effects of Paliperidone are tachycardia (a fast heartbeat), akathisia, somnolence, tremor, dystonia, cogwheel rigidity, anxiety, weight increase, dyspepsia, constipation and nasopharyngitis, among others.
Can I take Modesto XR 1.5 during pregnancy or while breastfeeding?
Paliperidone is a Pregnancy Category C medicine. There are no adequate and well-controlled studies in pregnant women, so it should be used during pregnancy only if the possible benefit justifies the possible risk to the fetus. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
What happens if I take too much Modesto XR 1.5?
Information on Paliperidone overdose is limited, and there is no specific antidote for it. If an overdose happens, the usual supportive measures are used, along with treatment for whatever symptoms appear. In an emergency call 999 or go to the nearest hospital emergency department.
How should I store Modesto XR 1.5?
Keep Paliperidone in a cool, dry place, away from light. Make sure children can't reach it.
Can I take other medicines with Modesto XR 1.5?
Some medicines can interact with Paliperidone, for example: Carbamazepine, Levodopa, Paliperidone Palmitate, Dopamine Hydrochloride. Tell your doctor or pharmacist about every medicine you take.
Do I need a prescription for Modesto XR 1.5?
Modesto XR 1.5 is a prescription (Rx) medicine. Take it as your doctor advises.