Informational only — Not medical advice. Always consult a licensed healthcare provider.

Community data Updated 23 hours ago

Indications

Omarigliptin is used to treat adults who have type 2 diabetes.

⚠️ Always consult a registered physician before taking any medicine.

Pharmacology

Omarigliptin is a long-acting inhibitor of the enzyme dipeptidyl peptidase-4 (DPP-4). This enzyme breaks down incretin hormones very quickly. Incretins help lower blood glucose after a meal, because they raise insulin and lower glucagon levels, and they do this only in response to glucose. By blocking DPP-4, Omarigliptin boosts the action of these incretin hormones.

Pregnancy & Breastfeeding

Nobody has tested omarigliptin in pregnant women in clinical trials. So it should be used during pregnancy only if the likely benefit to the mother justifies the possible risk to the fetus. Mothers who are taking omarigliptin should avoid breastfeeding.

⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

Dosage Reference

⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.

Adults: Omarigliptin tablets should be taken by mouth. The recommended dose of omarigliptin is 25 mg once weekly, either as monotherapy or as add-on therapy for optimisation of glycemic control. If a patient misses a dose, advise them to take the missed dose as soon as possible and then carry on with the regular weekly schedule. Never take two doses at one time. For renal impairment, the dose in patients with severe renal dysfunction, end-stage renal failure, or those who need hemodialysis or peritoneal dialysis should follow the values below. In severe end-stage kidney failure, men with CrCl>1.9 take 12.5 mg once a week, and women with CrCl >1.4 take 12.5 mg once a week. The safety and efficacy of omarigliptin in children and adolescents have not been established.

Side Effects & Interactions

Side Effects

No side-effect data recorded yet.