Norethisterone Acetate

Adults: Norethisterone Acetate is taken by mouth. It is not meant for use in children. Metropathia haemorrhagica (dysfunctional uterine bleeding): the dose is 1 tablet 3 times daily for 10 days. Bleeding usually stops within 1 to 3 days. A withdrawal bleeding like a normal period comes 2 to 4 days after treatment is stopped. Prophylaxis against recurrence of dysfunctional bleeding: if there are no signs that normal ovarian function has resumed, expect the bleeding to come back. The sign to look for is a rise in the morning temperature in the second half of the cycle, and the temperature should be measured daily. Cyclical bleeding can be established with 1 tablet twice daily from the 19th to the 26th day of the cycle. Premenstrual syndrome (including premenstrual mastalgia): symptoms such as headache, migraine, breast discomfort, water retention, tachycardia and psychological disturbances may ease with 2 to 3 tablets daily from the 19th to the 26th day of the cycle. Treatment should be repeated for several cycles. After it is stopped, the patient may stay symptom-free for a number of months. Postponement of menstruation: this is possible when menstrual bleeding is too frequent, and in special circumstances such as operations, travel or sports. Take 1 tablet of Norethisterone three times daily, starting 3 days before the expected onset of menstruation. A normal period should come 2 to 3 days after the patient stops taking the tablets. Endometriosis (pseudo-pregnancy therapy): long-term treatment starts on the 5th day of the cycle with 2 tablets of Norethisterone daily for the first few weeks. If spotting occurs, the dose is raised to 4 tablets daily and, if necessary, to 5 tablets daily. Once the bleeding has stopped, the initial dose is usually enough. Treatment lasts 4 to 6 months continuously, or longer if necessary. Menorrhagia (hypermenorrhoea): take 1 tablet 2 to 3 times a day from the 19th to the 26th day of the cycle, counting the first day of menstruation as day 1.