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All price changes →Remens
Rx5 mg • Tablet
Indications & Uses
Remens is indicated for:
Pharmacology
Norethisterone tablet contains Norethisterone, a progestogen that acts much like progesterone. It stops ovulation more strongly than progesterone does, and it also has weak estrogenic and androgenic properties. The tablet is used to treat a number of disorders of the menstrual cycle.
Norethisterone is absorbed from the gastrointestinal tract, and its effects last for at least 24 hours. The body excretes it in the urine.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Norethisterone Acetate is taken by mouth. It is not meant for use in children.
Metropathia haemorrhagica (dysfunctional uterine bleeding): the dose is 1 tablet 3 times daily for 10 days. Bleeding usually stops within 1 to 3 days. A withdrawal bleeding like a normal period comes 2 to 4 days after treatment is stopped.
Prophylaxis against recurrence of dysfunctional bleeding: if there are no signs that normal ovarian function has resumed, expect the bleeding to come back. The sign to look for is a rise in the morning temperature in the second half of the cycle, and the temperature should be measured daily. Cyclical bleeding can be established with 1 tablet twice daily from the 19th to the 26th day of the cycle.
Premenstrual syndrome (including premenstrual mastalgia): symptoms such as headache, migraine, breast discomfort, water retention, tachycardia and psychological disturbances may ease with 2 to 3 tablets daily from the 19th to the 26th day of the cycle. Treatment should be repeated for several cycles. After it is stopped, the patient may stay symptom-free for a number of months.
Postponement of menstruation: this is possible when menstrual bleeding is too frequent, and in special circumstances such as operations, travel or sports. Take 1 tablet of Norethisterone three times daily, starting 3 days before the expected onset of menstruation. A normal period should come 2 to 3 days after the patient stops taking the tablets.
Endometriosis (pseudo-pregnancy therapy): long-term treatment starts on the 5th day of the cycle with 2 tablets of Norethisterone daily for the first few weeks. If spotting occurs, the dose is raised to 4 tablets daily and, if necessary, to 5 tablets daily. Once the bleeding has stopped, the initial dose is usually enough. Treatment lasts 4 to 6 months continuously, or longer if necessary.
Menorrhagia (hypermenorrhoea): take 1 tablet 2 to 3 times a day from the 19th to the 26th day of the cycle, counting the first day of menstruation as day 1.
Side Effects
Side effects with Norethisterone Acetate are more common in the first few months after you start taking it, and they ease as treatment goes on. They are listed below by the part of the body they affect. Eye disorders: visual disturbance. GI disorders: nausea. General disorders and administration site conditions: headache, edema. Nervous system disorders: migraine. Respiratory, thoracic and mediastinal disorders: dyspnoea. Skin and subcutaneous tissue disorders: hypersensitivity (eg. rash, urticaria).
Cautions & Contraindications
Warnings & Precautions
There is a general opinion, based on statistical evidence, that users of combined oral contraceptives get venous thromboembolism and arterial thrombosis more often than non-users. This includes cerebral and myocardial infarction and subarachnoid haemorrhage. Full recovery from these disorders doesn't always happen, and in a few cases they are fatal. Norethisterone Acetate contains no oestrogen, but the possibility of an increased thromboembolic risk should still be considered. This applies particularly where there is a history of thromboembolic disease, or in severe diabetes with vascular changes or sickle-cell anaemia. Benign liver tumours have been seen in rare cases after use of hormonal substances such as the one in Norethisterone Acetate, and malignant ones in even rarer cases. In isolated cases these led to life-threatening intra-abdominal haemorrhage. If severe upper abdominal complaints, liver enlargement or signs of intra-abdominal haemorrhage occur, a liver tumour should be included in the differential diagnosis and, if necessary, the preparation should be withdrawn. Norethisterone Acetate can influence carbohydrate metabolism. In all diabetics, the parameters of carbohydrate metabolism should be examined carefully before treatment and regularly during it. Reasons for stopping Norethisterone Acetate immediately Occurrence for the first time of migrainous headaches or more frequent occurrence of unusually severe headaches, sudden perceptual disorders (e.g. disturbances of vision or hearing), first signs of thrombophlebitis or thromboembolic symptoms, feeling of pain and tightness in the chest, pending operations (six weeks beforehand), immobilisation (e.g. after accidents), onset of jaundice, hepatitis, general pruritus, significant rise in blood pressure, and pregnancy.
Contraindications
Norethisterone Acetate must not be used in pregnancy, in severe disturbances of liver function, or in Dubin-Johnson syndrome or Rotor syndrome. It is also not for people with previous or existing liver tumours, or a history during pregnancy of idiopathic jaundice, severe pruritus or herpes gestationis. Current thromboembolic processes and hypersensitivity to the active substances or to any of the excipients are also contraindications.
Pregnancy & Breastfeeding
Norethisterone acetate must not be used during pregnancy. It is also not suitable while a woman is breastfeeding, so Norethisterone should not be taken during lactation either.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Overdose
No overdose of Norethisterone Acetate has been reported, so treatment is usually not needed. There is no special antidote. If symptoms do appear, they are treated as they come.
⚠️ In an emergency call 999 or go to the nearest hospital emergency department.
Storage
Keep Norethisterone Acetate in a cool, dry place, below 30°C. Keep it out of reach of children.
Drug Interactions
Common questions about Remens 5 mg
What is Remens 5 mg Tablet?
Remens 5 mg Tablet is a medicine that contains Norethisterone Acetate. It is made by Popular Pharmaceuticals PLC. It belongs to the Drugs for menopausal symptoms: Hormone replacement therapy group of medicines.
What is Remens used for?
Remens is used for: Menstrual Disorder.
What are the side effects of Remens?
Side effects with Norethisterone Acetate are more common in the first few months after you start taking it, and they ease as treatment goes on. They are listed below by the part of the body they affect.
Can I take Remens during pregnancy or while breastfeeding?
Norethisterone acetate must not be used during pregnancy. It is also not suitable while a woman is breastfeeding, so Norethisterone should not be taken during lactation either. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
What happens if I take too much Remens?
No overdose of Norethisterone Acetate has been reported, so treatment is usually not needed. There is no special antidote. In an emergency call 999 or go to the nearest hospital emergency department.
How should I store Remens?
Keep Norethisterone Acetate in a cool, dry place, below 30°C. Keep it out of reach of children.
Can I take other medicines with Remens?
Some medicines can interact with Norethisterone Acetate, for example: Carbamazepine, Rifampicin, Oxcarbazepine, Griseofulvin, Primidone, Phenytoin. Tell your doctor or pharmacist about every medicine you take.
Is there a cheaper medicine with the same ingredient?
Remens is already among the lowest-priced brands of Norethisterone Acetate at this strength.
Do I need a prescription for Remens?
Remens is a prescription (Rx) medicine. Take it as your doctor advises.