Informational only — Not medical advice. Always consult a licensed healthcare provider.

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Community data Updated 2 months ago

Nefopam Hydrochloride

Non-Opioid Analgesics Prescription
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Indications

Pain Cancer

Neforex is indicated for the relief of acute pain, including post operative, dental, musculoskeletal and acute traumatic pain. It is also indicated for chronic pain such as cancer pain.

⚠️ Always consult a registered physician before taking any medicine.

Pharmacology

Nefopam Hydrochloride is a centrally acting pain reliever that starts working quickly. It seems to act mainly within the central nervous system, affecting both the brain and the spinal cord. Laboratory studies indicate that Nefopam blocks the re-uptake of several catecholamines, including noradrenaline, serotonin, and dopamine. This suggests that its pain-relieving effect may come, at least in part, from changing the levels of these neuromodulators in the brain and spinal cord.

Pregnancy & Breastfeeding

Nefopam Hydrochloride is not recommended for pregnant women. Evidence suggests that nefopam passes into human milk. A decision needs to be made about whether to stop breastfeeding or to stop the medicine. This should weigh the possible harm to the baby against how important the treatment is for the mother.

⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

Dosage Reference

⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.

Adults: Tablet Adults: the dose can range from 30 to 90 mg three times daily, depending on how the patient responds. The recommended starting dose of Nefopam Hydrochloride is 2 tablets three times daily. Elderly: older patients may need a lower dose because their metabolism is slower. It is strongly recommended that the starting dose does not go above 1 tablet 3 times daily. Injection Adults: 20 mg by IM injection, repeated every 6 hours if necessary. It can also be given by slow IV injection in a similar dose. Children: Nefopam Hydrochloride is not recommended for children under 12 years of age.