Indications
Moxifloxacin and Dexamethasone eye drop is used to treat eye infections caused by susceptible microorganisms. Doctors also use it after eye surgery, to prevent the inflammation and bacterial infection that can follow.
⚠️ Always consult a registered physician before taking any medicine.
Pharmacology
Moxifloxacin is a broad spectrum, 4th generation fluorinated quinolone. It blocks two enzymes, topoisomerase II (DNA gyrase) and topoisomerase IV. DNA gyrase is an essential enzyme in the replication, transcription and repair of bacterial DNA. Topoisomerase IV is known to play a key role in partitioning the chromosomal DNA when a bacterial cell divides.
Dexamethasone is a cortisone derivative with high activity, which comes from the methyl group in the 16-alpha position and the fluorine atom in the 9-alpha position. Like other glucocorticoids, it is anti-allergic, anti-exudative and anti-proliferative. It works by inhibiting phospholipase A2, the first step in prostaglandin synthesis. Dexamethasone also inhibits the chemotactic infiltration of neutrophils into the site of inflammation.
Pregnancy & Breastfeeding
No adequate and well-controlled studies have been done in pregnant women. So Moxifloxacin and Dexamethasone combination eye drops should be used in pregnancy only if the likely benefit justifies the possible risk to the fetus. Take care when the eye drops are given to women who are breastfeeding.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Dosage Reference
⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.