Informational only — Not medical advice. Always consult a licensed healthcare provider.

Community data Updated 23 hours ago

Indications

Methocarbamol tablet is used alongside rest, physical therapy and other measures to relieve the discomfort of acute, painful musculoskeletal conditions. Nobody has clearly identified how methocarbamol works, though it may be linked to its sedative properties. It does not directly relax tense skeletal muscles in man.

⚠️ Always consult a registered physician before taking any medicine.

Pharmacology

Methocarbamol is thought to work through its depressant effect on the central nervous system. This may happen in a few ways: it may block spinal polysynaptic reflexes, reduce nerve transmission in the spinal and supraspinal polysynaptic pathways, and lengthen the refractory period of muscle cells. Studies have found that methocarbamol has no effect on the contraction of muscle fibres, motor end plates or nerve fibres.

Pregnancy & Breastfeeding

Methocarbamol is Pregnancy Category C. No animal reproduction studies have been done with it, so nobody knows whether it can harm the baby when given to a pregnant woman, or whether it can affect a woman's ability to reproduce. It should be given to a pregnant woman only if it is clearly needed.

Methocarbamol and/or its metabolites pass into the milk of dogs. It isn't known whether Methocarbamol or its metabolites pass into human milk. Many drugs do pass into human milk, so caution should be exercised when Methocarbamol is given to a nursing woman.

⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

Dosage Reference

⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.

Adults: Route of administration: oral. Methocarbamol 500 mg, for adults. The starting dose is 3 tablets q.i.d. The maintenance dose is 2 tablets q.i.d. Methocarbamol 750 mg, for adults. The starting dose is 2 tablets q.i.d. The maintenance dose is 1 tablet q.4h. or 2 tablets t.i.d. Six grams a day are recommended for the first 48 to 72 hours of treatment, and for severe conditions 8 grams a day may be given. After that, the dose can usually be reduced to about 4 grams a day. Pediatric use: the safety and effectiveness of Methocarbamol in patients below the age of 16 have not been established.

Side Effects & Interactions

Side Effects

No side-effect data recorded yet.