Methocarbamol 500 mg

Methocarbamol is thought to work through its depressant effect on the central nervous system. This may happen in a few ways: it may block spinal polysynaptic reflexes, reduce nerve transmission in the spinal and supraspinal polysynaptic pathways, and lengthen the refractory period of muscle cells. Studies have found that methocarbamol has no effect on the contraction of muscle fibres, motor end plates or nerve fibres.

Methocarbamol is Pregnancy Category C. No animal reproduction studies have been done with it, so nobody knows whether it can harm the baby when given to a pregnant woman, or whether it can affect a woman's ability to reproduce. It should be given to a pregnant woman only if it is clearly needed.

Methocarbamol and/or its metabolites pass into the milk of dogs. It isn't known whether Methocarbamol or its metabolites pass into human milk. Many drugs do pass into human milk, so caution should be exercised when Methocarbamol is given to a nursing woman.

There isn't much information on the acute toxicity of Methocarbamol. Overdose with Methocarbamol often happens together with alcohol or other CNS depressants, and the symptoms include nausea, drowsiness, blurred vision, hypotension, seizures and coma. Since the medicine came on the market, deaths have been reported after an overdose of Methocarbamol alone, and also when it was taken with other CNS depressants, alcohol or psychotropic drugs.

The management of overdose is symptomatic and supportive. Supportive measures include keeping an adequate airway, monitoring urinary output and vital signs, and giving intravenous fluids if necessary. Whether hemodialysis helps in managing an overdose is unknown.

Keep Methocarbamol away from light and store it below 30°C. Always keep the medicine out of the reach of children.