Meropenem Trihydrate

Adults: Meropenem Trihydrate is dosed according to the type and severity of the infection and the condition of the patient, and the same factors decide how long treatment runs. The recommended doses are as follows. Adults: the usual dose is 500 mg to 1 gm given by intravenous administration every 8 hours. Pneumonia, urinary tract infections, gynaecological infections such as endometritis and pelvic inflammatory disease, and skin and skin structure infections: 500 mg IV every 8 hours. Nosocomial pneumonias, peritonitis, presumed infections in neutropenic patients and septicaemia: 1 g IV every 8 hours. Intra-abdominal infections: 500 mg to 1 gm every 8 hours. Cystic fibrosis: up to 2 gm every 8 hours. Meningitis: 2 gm IV every 8 hours. Children aged 3 months to 12 years: 10 to 40 mg/kg intravenously every 8 hours. The exact dose depends on the type and severity of the infection, how susceptible the pathogens are, and the condition of the patient. Intra-abdominal infections: 20 mg/kg every 8 hours. Cystic fibrosis (4 to 18 years): 25 to 40 mg/kg every 8 hours. Meningitis: 40 mg/kg IV every 8 hours. Febrile neutropenia: 20 mg/kg every 8 hours. Children over 50 kg in weight should take the adult dose. There is no experience of using Meropenem Trihydrate in children with hepatic or renal impairment.