Pricing
Prices are indicative MRP and may vary by pharmacy. Trend compares against the last recorded price.
All price changes →More from Merovent
Other strengths and forms by DBL Pharmaceuticals Limited
Indications & Uses
Merovent is indicated for:
Pharmacology
Meropenem is a carbapenem antibiotic given by injection or infusion (parenteral use). It kills bacteria by interfering with the synthesis of their cell wall. The original sentence on how it works is a bit broken, but it says that meropenem penetrates bacterial cell walls, is highly stable against all serine beta-lactamases, and has a marked affinity for the Penicillin Binding Proteins (PBPs). Meropenem is strongly bactericidal against a broad spectrum of Gram-positive and Gram-negative bacteria, both aerobic and anaerobic.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Meropenem Trihydrate is dosed according to the type and severity of the infection and the condition of the patient, and the same factors decide how long treatment runs. The recommended doses are as follows.
Adults: the usual dose is 500 mg to 1 gm given by intravenous administration every 8 hours.
Pneumonia, urinary tract infections, gynaecological infections such as endometritis and pelvic inflammatory disease, and skin and skin structure infections: 500 mg IV every 8 hours.
Nosocomial pneumonias, peritonitis, presumed infections in neutropenic patients and septicaemia: 1 g IV every 8 hours.
Intra-abdominal infections: 500 mg to 1 gm every 8 hours.
Cystic fibrosis: up to 2 gm every 8 hours.
Meningitis: 2 gm IV every 8 hours.
Children aged 3 months to 12 years: 10 to 40 mg/kg intravenously every 8 hours. The exact dose depends on the type and severity of the infection, how susceptible the pathogens are, and the condition of the patient.
Intra-abdominal infections: 20 mg/kg every 8 hours.
Cystic fibrosis (4 to 18 years): 25 to 40 mg/kg every 8 hours.
Meningitis: 40 mg/kg IV every 8 hours.
Febrile neutropenia: 20 mg/kg every 8 hours.
Children over 50 kg in weight should take the adult dose. There is no experience of using Meropenem Trihydrate in children with hepatic or renal impairment.
Side Effects
Most people tolerate Meropenem Trihydrate well. Some may have inflammation, thrombophlebitis or pain at the site of injection. Skin reactions such as rash, pruritus and urticaria can also occur, as can abdominal pain, nausea, vomiting, diarrhea and headache.
Cautions & Contraindications
Warnings & Precautions
If an allergic reaction to Meropenem Trihydrate happens, stop the medicine and take the right measures for the reaction. In patients with liver disease, Meropenem Trihydrate should be used with careful monitoring of transaminase and bilirubin levels.
Contraindications
Meropenem must not be given to anyone who has shown hypersensitivity to it.
Pregnancy & Breastfeeding
Meropenem Trihydrate is Pregnancy Category B. There are no adequate and well-controlled studies in pregnant women, so the medicine should be used during pregnancy only if it is clearly needed. Many drugs pass into human milk, so a nursing mother should be given Meropenem with caution.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Use in Special Populations
Renal impairment: The dose of Meropenem Trihydrate should be reduced in patients whose creatinine clearance is less than 51 ml/min.
Hepatic impairment: No dose adjustment is needed when liver function is impaired.
Hemodialysis patients should get Meropenem Trihydrate after the dialysis has been completed.
Elderly: No dose adjustment is needed in elderly patients, unless creatinine clearance is <51 ml/min.
Use in children: Efficacy and tolerability in infants under 3 months have not been established.
Overdose
An accidental overdose of Meropenem Trihydrate can happen during treatment, especially in patients with renal impairment. Treatment is symptomatic. In people with normal kidney function, the body clears the medicine quickly through the kidneys. In those with renal impairment, haemodialysis will remove Meropenem Trihydrate and its metabolite.
⚠️ In an emergency call 999 or go to the nearest hospital emergency department.
Storage
Store the Meropenem Trihydrate vials in a cool, dry place below 30oC, away from light and moisture. Keep them out of the reach of children.
Drug Interactions
Common questions about Merovent 1 gm
What is Merovent 1 gm IV Injection or Infusion?
Merovent 1 gm IV Injection or Infusion is a medicine that contains Meropenem Trihydrate. It is made by DBL Pharmaceuticals Limited. It belongs to the Other beta-lactam antibiotics group of medicines.
What is Merovent used for?
Merovent is used for: Pneumonia, Skin and Soft Tissue Infection, Sepsis.
What are the side effects of Merovent?
Most people tolerate Meropenem Trihydrate well. Some may have inflammation, thrombophlebitis or pain at the site of injection.
Can I take Merovent during pregnancy or while breastfeeding?
Meropenem Trihydrate is Pregnancy Category B. There are no adequate and well-controlled studies in pregnant women, so the medicine should be used during pregnancy only if it is clearly needed. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
What happens if I take too much Merovent?
An accidental overdose of Meropenem Trihydrate can happen during treatment, especially in patients with renal impairment. Treatment is symptomatic. In an emergency call 999 or go to the nearest hospital emergency department.
How should I store Merovent?
Store the Meropenem Trihydrate vials in a cool, dry place below 30oC, away from light and moisture. Keep them out of the reach of children.
Can I take other medicines with Merovent?
Some medicines can interact with Meropenem Trihydrate, for example: Meropenem, Valproic Acid. Tell your doctor or pharmacist about every medicine you take.
Do I need a prescription for Merovent?
Merovent is a prescription (Rx) medicine. Take it as your doctor advises.