Informational only — Not medical advice. Always consult a licensed healthcare provider.

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Community data Updated 2 months ago
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Indications

Hypertension

Lispril is indicated for the treatment of essential hypertension of all grades and for renovascular hypertension. It may be used alone or in combination with other antihypertensive agents.

⚠️ Always consult a registered physician before taking any medicine.

Pharmacology

Lisinopril works by blocking the enzyme ACE, which normally turns angiotensin I into angiotensin II, a powerful vasoconstrictor (a substance that narrows blood vessels). With less angiotensin II around, plasma renin activity goes up and the secretion of aldosterone (a hormone that makes the body hold on to water and Na) goes down. The blood vessels relax and widen, which helps lower BP.

Pregnancy & Breastfeeding

Pregnancy Category C (FDA classification).

⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

Dosage Reference

⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.

Adults: Treatment should begin with 2.5 mg once daily. For patients with uncomplicated essential hypertension who are not taking a diuretic, the recommended starting dose is 10 mg once daily. The dose should then be adjusted according to the blood pressure response. The usual dosage range is 10 to 20 mg once daily. The maximum dose is 40 mg per day, taken as a single dose, or as directed by the physician. Patients on diuretics: In hypertensive patients who are currently taking a diuretic, symptomatic hypotension may occur, occasionally after the first dose of Lisinopril. If the diuretic cannot be stopped, a starting dose of 10 mg should be given under medical supervision for at least two hours, and then for at least one further hour after blood pressure has stabilised.

Side Effects & Interactions

Side Effects

No side-effect data recorded yet.