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Other brands with the same active ingredient
These brands contain the same active ingredient (Lisinopril). Same strength and form. Confirm the switch with your doctor or pharmacist.
More from Sinopril
Other strengths and forms by Square Pharmaceuticals PLC, Pabna
Indications & Uses
Sinopril is indicated for:
Pharmacology
Lisinopril works by blocking the enzyme ACE, which normally turns angiotensin I into angiotensin II, a powerful vasoconstrictor (a substance that narrows blood vessels). With less angiotensin II around, plasma renin activity goes up and the secretion of aldosterone (a hormone that makes the body hold on to water and Na) goes down. The blood vessels relax and widen, which helps lower BP.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Treatment should begin with 2.5 mg once daily. For patients with uncomplicated essential hypertension who are not taking a diuretic, the recommended starting dose is 10 mg once daily. The dose should then be adjusted according to the blood pressure response. The usual dosage range is 10 to 20 mg once daily. The maximum dose is 40 mg per day, taken as a single dose, or as directed by the physician.
Patients on diuretics: In hypertensive patients who are currently taking a diuretic, symptomatic hypotension may occur, occasionally after the first dose of Lisinopril. If the diuretic cannot be stopped, a starting dose of 10 mg should be given under medical supervision for at least two hours, and then for at least one further hour after blood pressure has stabilised.
Side Effects
Chest discomfort, flushing, low blood pressure, a fast heartbeat, abdominal pain, loss of appetite, constipation, wind, joint pain, depression, difficulty sleeping, bronchitis and cough may occur.
Cautions & Contraindications
Warnings & Precautions
Kidney function should be checked before starting Lispril and monitored during treatment. Use with caution in patients with impaired kidney function, as they may need lower doses. Severe low blood pressure has been reported with ACE inhibitors, mainly in patients with severe heart failure and in those undergoing surgery. Lispril should not be used in patients with aortic stenosis, cor pulmonale, or outflow tract obstruction. It is not known whether Lispril passes into breast milk, so caution is advised when giving it to breastfeeding mothers.
Contraindications
Lisinopril should not be used in people who are allergic to it, or in anyone who has previously developed angioedema (severe swelling of the face, lips, tongue or throat) while taking an ACE inhibitor. It must also not be used during pregnancy.
Pregnancy & Breastfeeding
Pregnancy Category C (FDA classification).
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Storage
Store Lisinopril below 30°C, and keep it away from light and moisture. Keep it out of the reach of children.
Drug Interactions
Common questions about Sinopril 5 mg
What is Sinopril 5 mg Tablet?
Sinopril 5 mg Tablet is a medicine that contains Lisinopril. It is made by Square Pharmaceuticals PLC, Pabna. It belongs to the Angiotensin-converting enzyme (ACE) inhibitors group of medicines.
What is Sinopril used for?
Sinopril is used for: Hypertension.
What are the side effects of Sinopril?
Chest discomfort, flushing, low blood pressure, a fast heartbeat, abdominal pain, loss of appetite, constipation, wind, joint pain, depression, difficulty sleeping, bronchitis and cough may occur.
Can I take Sinopril during pregnancy or while breastfeeding?
Pregnancy Category C (FDA classification). Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
How should I store Sinopril?
Store Lisinopril below 30°C, and keep it away from light and moisture. Keep it out of the reach of children.
Can I take other medicines with Sinopril?
Some medicines can interact with Lisinopril, for example: Telmisartan + Hydrochlorothiazide. Tell your doctor or pharmacist about every medicine you take.
Do I need a prescription for Sinopril?
Sinopril is a prescription (Rx) medicine. Take it as your doctor advises.