Indications
Nodia is used in adults to treat active rheumatoid arthritis (RA). It helps reduce the signs and symptoms of the disease and slows the structural joint damage seen on x-ray, such as erosions and narrowing of the joint space.
⚠️ Always consult a registered physician before taking any medicine.
Pharmacology
Leflunomide is an isoxazole immunomodulatory medicine. It works by blocking de novo pyrimidine synthesis, which slows the growth of cells. After you take it by mouth, the body breaks it down quickly into A771726. This compound is active in laboratory tests, and it is thought to be the form that does the work in the body. In animal models of autoimmune disease, leflunomide has shown both preventive and treatment effects. It has also shown anti-inflammatory action, along with weak pain-relieving and fever-reducing effects. In a model of experimental septicaemia, leflunomide did not change how well mice could resist bacterial infection.
Pregnancy & Breastfeeding
Leflunomide is not recommended for women who are pregnant. Pregnancy must be avoided both during treatment with leflunomide and for some time afterward, until the drug elimination procedure has been completed following treatment. Leflunomide should also not be used by breastfeeding mothers. It is not known whether the drug passes into human breast milk, but since many medicines do, and since leflunomide could potentially cause serious harm to a nursing infant, the decision to continue breastfeeding or to start leflunomide treatment should weigh how important the medicine is to the mother's health.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Dosage Reference
⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.
Side Effects & Interactions
Side Effects
No side-effect data recorded yet.